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Human Reproduction, Vol. 6, No. 5, pp. 672-675, 1991
© 1991 European Society of Human Reproduction and Embryology

other

Transvaginal intratubal embryo transfer: a new treatment of male infertility

Klaus Diedrich1, Ottmar Bauer, Andreas Werner, Hans van der Ven, Safaa Al-Hasani and Dieter Krebs

Department of Obstetrics and Gynaecology, University of Bonn 5300 Bonn, FRG

Correspondence: 1To whom correspondence should be addressed

Intratubal embryo transfer is a new method in the treatment of human infertility. Following transvaginal sonographic oocyte retrieval, in-vitro fertilization (IVF) is performed and embryos are transferred into the Fallopian tube transvaginally. In comparison with gamete intra-Fallopian transfer (GIFT), fertilization under in vitro conditions offers the advantage that the success of the fertilization process can be examined. Therefore, this method can give important diagnostic information, especially in cases of poor sperm quality or unexplained infertility. After fertilization in vitro and transfer into the tube, embryonic development occurs in the physiological milieu of the oviduct. Transvaginal intratubal embryo transfer was perfonned in 95 patients with male factor infertility. In 29 cases (31%), a pregnancy was achieved. One abortion, but no ectopic pregnancy was observed. This method combines the advantages of IVF and GIFT and offers a successful procedure for the treatment of infertility.

Key words: tubal embryo transfer/transvaginal route/in-vitro fertilization/male infertility


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