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Human Reproduction, Vol. 7, No. suppl_1, pp. 85-88, 1992
© 1992 European Society of Human Reproduction and Embryology

Indications for oocyte donation

P.N. Barri1, B. Coroleu, F. Martinez, N. Parera, A. Veiga, G. Calderón, M. Boada and I. Belil

Service of Reproductive Medicine, Department of Obstetrics and Gynaecology, Institut Universitari Dexeus Passeig Bonanova 67, 08017 Barcelona, Spain

Correspondence: 1To whom correspondence should be addressed

Donated oocytes were transferred on 92 occasions to 87 women without gonadal function and 5 with functional ovaries. Twenty-three pregnancies were established (25% pregnancy rate), 9 after transfer of fresh embryos in 30 synchronous donor and recipient cycles and 14 after transfers of frozen-thawed embryos in 62 asynchronous donor and recipient cycles. Twenty-two pregnancies were obtained in agonadal patients (25.3% pregnancy rate) and 1 in a gonadal woman (20% pregnancy rate). Pregnant women were younger than those who did not become pregnant, but the difference was not significant. The pregnancy rate was higher when intra-Fallopian transfer was performed (46%) as compared with intrauterine transfer (21.5%) and when micronized progesterone was given intravaginally (pregnancy rate 30.3%) as compared to instramuscularly injected natural progesterone in oil (pregnancy rate 22%). Twenty healthy infants have been born including one set of twins; four pregnancies miscarried.

Key words: Embryo transfer/intra-Fallopian transfer/intrauterine transfer/oocyte donation/ovarian failure


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