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Human Reproduction, Vol. 8, No. 12, pp. 2075-2079, 1993
© 1993 European Society of Human Reproduction and Embryology

review-article

Infertility: Metastatic ovarian strumosis in an in-vitro fertilization patient

Juan Balasch1,2, Jaime Pahisa1, Manuel Márquez3, Jaime Ordi3, Francisco Fábregues1, Bienvenido Puerto1 and Juan A. Vanrell1

1Department of Obstetrics and Gynaecology, Hospital Clínic i Provincial Barcelona, Spain 3Department of Pathology, Faculty of Medicine, University of Barcelona, Hospital Clínic i Provincial Barcelona, Spain

Correspondence: 2To whom correspondence should be addressed at: Department of Obstetrics and Gynaecology, Hospital Clínic i Provincial, C/Casanova 143, 08036-Barcelona, Spain

Malignant struma ovarii is a very rare tumour, with considerable controversy concerning the necessary histologic features for malignancy. Still more infrequent is the condition termed ‘metastatic ovarian strumosis’ or simply ‘benign strumosis or strumatosis’ and characterized by the presence of peritoneal implants of mature thyroid tissue occurring in struma ovarii. ‘Strumosis’ should not be confused with malignancy. Presented is a case of ‘metastatic ovarian strumosis’ in a 36-year-old woman with primary infertility who underwent three in-vitro fertilization (IVF) cycles with ovarian stimulation. She received hormonal treatment for 6 months after her last IVF because of ‘persistent enlarged ovarian follicles’ which were in fact ‘thyroid follicles’.

Key words: IVF/ovarian stimulation/ovarian strumosis/persistent ovarian cyst/struma ovarii


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