Human Reproduction, Vol. 8, No. 7, pp. 1061-1066, 1993
© 1993 European Society of Human Reproduction and Embryology
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High fertilization and implantation rates after intracytoplasmic sperm injection
Centre for Reproductive Medicine, Academisch Ziekenhuis VUB Laarbeeklaan 101, B-1090 Brussels, Belgium
Correspondence: 1To whom correspondence should be addressed
Previously reported better fertilization rate after intra-cytoplasmic single sperm injection (ICSI) than after subzonal insemination of several spermatozoa was confirmed in a controlled comparison of the two procedures in 11 patients. Intracytoplasmic sperm injection was carried out in 150 consecutive treatment cycles of 150 infertile couples, who had failed to have fertilized oocytes after standard in-vitro fertilization (IVF) procedures or who were not accepted for IVF because not enough motile spermatozoa were present in the ejaculate. A single spermatozoon was injected into the ooplasm of 1409 metaphase II oocytes. Only 117 oocytes (8.3%) were damaged by the procedure and 830 oocytes (64.2% of the successfully injected oocytes) had two distinct pronuclei the morning after the injection procedure. The fertilization rate was not influenced by semen characteristics. After 24 h of further in-vitro culture, 71.2% of these oocytes developed into embryos, which were transferred or cryopreserved. Only 15 patients did not have embryos replaced. Three-quarters of the transfers were triple-embryo transfers. High pregnancy rates were noticed since 67 pregnancies were achieved, of which 53 were clinical, i.e. a total and clinical pregnancy rate of 44.7% and 35.3% per started cycle and 49.6% and 39.2% per embryo transfer. A total of 237 supernumerary embryos were cryopreserved in 71 treatment cycles.
Key words: intracytoplasmic injection/in-vitro fertilization/malefactor infertility/oocyte/spermatozoon
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|
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|
|
|
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|
|
|
|
|
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|
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|
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|
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|
|
|
|
|
|
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|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
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|
|
|
|
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|
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|
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|
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|
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|
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|
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|
|
|
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|
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|
|
|
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|
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|
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|
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|
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H. Murphy, C. George, D. de Kretser, and S. Judd Successful treatment with ICSI of infertility caused by azoospermia associated with adrenal rests in the testes: Case report Hum. Reprod., February 1, 2001; 16(2): 263 - 267. [Abstract] [Full Text] [PDF]
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J. C.M. Dumoulin, E. Coonen, M. Bras, J.M. Bergers-Janssen, R. C.M. Ignoul-Vanvuchelen, L. C.P. van Wissen, J. P.M. Geraedts, and J. L.H. Evers Embryo development and chromosomal anomalies after ICSI: effect of the injection procedure Hum. Reprod., February 1, 2001; 16(2): 306 - 312. [Abstract] [Full Text] [PDF]
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A.D. Esterhuizen, D.R. Franken, J.G.H. Lourens, and L.H. van Rooyen Clinical importance of zona pellucida-induced acrosome reaction and its predictive value for IVF Hum. Reprod., January 1, 2001; 16(1): 138 - 144. [Abstract] [Full Text] [PDF]
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H. Yazawa, K. Yanagida, H. Katayose, S. Hayashi, and A. Sato Comparison of oocyte activation and Ca2+ oscillation-inducing abilities of round/elongated spermatids of mouse, hamster, rat, rabbit and human assessed by mouse oocyte activation assay Hum. Reprod., December 1, 2000; 15(12): 2582 - 2590. [Abstract] [Full Text] [PDF]
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C. Wittemer, K. Bettahar-Lebugle, J. Ohl, C. Rongieres, I. Nisand, and P. Gerlinger Zygote evaluation: an efficient tool for embryo selection Hum. Reprod., December 1, 2000; 15(12): 2591 - 2597. [Abstract] [Full Text] [PDF]
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J. Ramalho-Santos, P. Sutovsky, C. Simerly, R. Oko, G. M. Wessel, L. Hewitson, and G. Schatten ICSI choreography: fate of sperm structures after monospermic rhesus ICSI and first cell cycle implications Hum. Reprod., December 1, 2000; 15(12): 2610 - 2620. [Abstract] [Full Text] [PDF]
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R. Anniballo, F. Ubaldi, L. Cobellis, M. Sorrentino, L. Rienzi, E. Greco, and J. Tesarik Criteria predicting the absence of spermatozoa in the Sertoli cell-only syndrome can be used to improve success rates of sperm retrieval Hum. Reprod., November 1, 2000; 15(11): 2269 - 2277. [Abstract] [Full Text] [PDF]
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S. J. Silber Microsurgical TESE and the distribution of spermatogenesis in non-obstructive azoospermia Hum. Reprod., November 1, 2000; 15(11): 2278 - 2284. [Abstract] [Full Text] [PDF]
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D.I. Lewis-Jones, M.R. Gazvani, and R. Mountford Cystic fibrosis in infertility: screening before assisted reproduction: Opinion Hum. Reprod., November 1, 2000; 15(11): 2415 - 2417. [Abstract] [Full Text] [PDF]
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 M. P. Mayorga, J. Gromoll, H. M. Behre, C. Gassner, E. Nieschlag, and M. Simoni Ovarian Response to Follicle-Stimulating Hormone (FSH) Stimulation Depends on the FSH Receptor Genotype J. Clin. Endocrinol. Metab., September 1, 2000; 85(9): 3365 - 3369. [Abstract] [Full Text]
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K.L. Larson, C.J. DeJonge, A.M. Barnes, L.K. Jost, and D.P. Evenson Sperm chromatin structure assay parameters as predictors of failed pregnancy following assisted reproductive techniques Hum. Reprod., August 1, 2000; 15(8): 1717 - 1722. [Abstract] [Full Text] [PDF]
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R. Mercan, B. Urman, C. Alatas, S. Aksoy, A. Nuhoglu, A. Isiklar, and B. Balaban Outcome of testicular sperm retrieval procedures in non-obstructive azoospermia: percutaneous aspiration versus open biopsy Hum. Reprod., July 1, 2000; 15(7): 1548 - 1551. [Abstract] [Full Text] [PDF]
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T.A. Griffiths, A.P. Murdoch, and M. Herbert Embryonic development in vitro is compromised by the ICSI procedure Hum. Reprod., July 1, 2000; 15(7): 1592 - 1596. [Abstract] [Full Text] [PDF]
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I. De Croo, J. Van der Elst, K. Everaert, P. De Sutter, and M. Dhont Fertilization, pregnancy and embryo implantation rates after ICSI in cases of obstructive and non-obstructive azoospermia Hum. Reprod., June 1, 2000; 15(6): 1383 - 1388. [Abstract] [Full Text] [PDF]
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S. Ogawa, S. Araki, Y. Araki, M. Ohno, and I. Sato Chromosome analysis of human spermatozoa from an oligoasthenozoospermic carrier for a 13;14 Robertsonian translocation by their injection into mouse oocytes Hum. Reprod., May 1, 2000; 15(5): 1136 - 1139. [Abstract] [Full Text] [PDF]
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D.Y. Liu and H.W.G. Baker Defective sperm-zona pellucida interaction: a major cause of failure of fertilization in clinical in-vitro fertilization Hum. Reprod., March 1, 2000; 15(3): 702 - 708. [Abstract] [Full Text] [PDF]
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E. Van den Abbeel and A. Van Steirteghem Zona pellucida damage to human embryos after cryopreservation and the consequences for their blastomere survival and in-vitro viability Hum. Reprod., February 1, 2000; 15(2): 373 - 378. [Abstract] [Full Text] [PDF]
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J. C.M. Dumoulin, E. Coonen, M. Bras, L. C.P. van Wissen, R. Ignoul-Vanvuchelen, J.M. Bergers-Jansen, J. G. Derhaag, J. P.M. Geraedts, and J. L.H. Evers Comparison of in-vitro development of embryos originating from either conventional in-vitro fertilization or intracytoplasmic sperm injection Hum. Reprod., February 1, 2000; 15(2): 402 - 409. [Abstract] [Full Text] [PDF]
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T. Ebner, C. Yaman, M. Moser, M. Sommergruber, O. Feichtinger, and G. Tews Prognostic value of first polar body morphology on fertilization rate and embryo quality in intracytoplasmic sperm injection Hum. Reprod., February 1, 2000; 15(2): 427 - 430. [Abstract] [Full Text] [PDF]
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 R. C. Pinheiro, J. Lambert, F. Benard, F. Mauffette, and P. Miron Effectiveness of in vitro fertilization with intracytoplasmic sperm injection for severe male infertility Can. Med. Assoc. J., November 1, 1999; 161(11): 1397 - 1401. [Abstract] [Full Text] [PDF]
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A. Kamal, R. Mansour, I. Fahmy, G. Serour, C. Rhodes, and M. Aboulghar Easily decapitated spermatozoa defect: a possible cause of unexplained infertility Hum. Reprod., November 1, 1999; 14(11): 2791 - 2795. [Abstract] [Full Text] [PDF]
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F. Ubaldi, Z. P. Nagy, L. Rienzi, J. Tesarik, R. Anniballo, G. Franco, F. Menchini-Fabris, and E. Greco Reproductive capacity of spermatozoa from men with testicular failure Hum. Reprod., November 1, 1999; 14(11): 2796 - 2800. [Abstract] [Full Text] [PDF]
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D. M. de Kretser and H. W. G. Baker Infertility in Men: Recent Advances and Continuing Controversies J. Clin. Endocrinol. Metab., October 1, 1999; 84(10): 3443 - 3450. [Full Text] [PDF]
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C. Krausz, L. Quintana-Murci, S. Barbaux, J.-P. Siffroi, H. Rouba, D. Delafontaine, N. Souleyreau-Therville, G. Arvis, J. M. Antoine, E. Erdei, et al. A High Frequency of Y Chromosome Deletions in Males with Nonidiopathic Infertility J. Clin. Endocrinol. Metab., October 1, 1999; 84(10): 3606 - 3612. [Abstract] [Full Text] [PDF]
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C. Staessen, M. Camus, K. Clasen, A. De Vos, and A. Van Steirteghem Conventional in-vitro fertilization versus intracytoplasmic sperm injection in sibling oocytes from couples with tubal infertility and normozoospermic semen Hum. Reprod., October 1, 1999; 14(10): 2474 - 2479. [Abstract] [Full Text] [PDF]
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