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Human Reproduction, Vol. 8, No. 8, pp. 1284-1287, 1993
© 1993 European Society of Human Reproduction and Embryology

research-article

Pregnancy: Analysis of the risk factors with regard to the occurrence of ectopic pregnancy after medically assisted procreation

Guy Verhulst1, Michel Camus, Nico Bollen, André Van Steirteghem and Paul Devroey

Centre for Reproductive Medicine, University Hospital, Dutch-speaking Brussels Free University (Vrije Universiteit Brussel) Laarbeeklaan 101, B-1090 Brussels, Belgium

Correspondence: 1To whom correspondence should be addressed

In a retrospective study (1985–1989) based on data from the Centre for Reproductive Medicine in Brussels, a total of 23 ectopic pregnancies (2.24%) occurred after 3800 embryo, zygote or gamete transfers. This number was low compared with the data published elsewhere. Tubal damage was a major risk factor towards developing an ectopic pregnancy after in-vitro fertilization and embryo transfer. The number of ectopic pregnancies after the association of clomiphene citrate and human menopausal gonadotrophin (HMG) was significantly higher in patients with tubal (7.8%) and non-tubal indications (2.1%) compared with those stimulated with gonadotrophin-releasing hormone (GnRH) and HMG (2.18% and 0.84%, respectively). The number of replaced embryos was not associated with the rate of ectopic pregnancy and neither did transfer technique (intra-uterine or intra-Fallopian transfer) influence the ectopic pregnancy rate.

Key words: ectopic pregnancy/embryo transfer/Fallopian tube/risk factor


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