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Human Reproduction, Vol. 9, No. suppl_1, pp. 195-201, 1994
© 1994 European Society of Human Reproduction and Embryology

Laboratory evidence for the hormonal dependency of meningiomas

Jeffrey J. Olson

The Emory Clinic, Department of Neurosurgery 1327 Clifton Road, N.E., Atlanta GA 30322, USA

Evidence for the hormonal dependency of meningiomas and of the value of various forms of endocrine therapy are described. Clinical features of the tumour are described. Laboratory evidence for the presence and activity of functional steroid receptors is described, and their characteristics are analysed. The effect of receptor antagonists on the growth of the tumour cells is indicated.

Key words: meningioma/steroids/steroid recptors/therapy


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