The use of blastocyst culture to avoid inheritance of an abnormal paternal genome after ICSI

doi:10.1093/humrep/14.1.4

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Human Reproduction, Vol. 14, No. 1, 4-5, January 1999
© 1999 European Society of Human Reproduction and Embryology

Debate

The use of blastocyst culture to avoid inheritance of an abnormal paternal genome after ICSI

Denny Sakkas

Assisted Conception Unit, Birmingham Women's Hospital and Reproductive Biology and Genetics Group, University of Birmingham, Edgbaston, Birmingham B15 2TG, UK

The development of suitable defined sequential culture mediamethods that can reliably lead to high rates of blastocyst developmentin human in-vitro fertilization (IVF) (Gardner et al., 1998a)has brought about the dilemma of when to apply this technique.As with many new IVF techniques, a choice must be made by manyreproductive units of whether or not to adopt a new technologywithout compromising the ultimate goal of achieving pregnanciesfor couples.

Gardner et al. (1998a,b) have stated that one . . . [Full Text of this Article]

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