Human Reproduction, Vol. 14, No. 10, 2421-2422,
October 1999
© 1999 European Society of Human Reproduction and Embryology
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Severe OHSS: Decreasing the risk of severe ovarian hyperstimulation syndrome
Department of Obstetrics and Gynecology, PO Box 35295, Jordan University Hospital, Amman-11180, Jordan
Ovarian hyperstimulation syndrome (OHSS) is the most serious complication of ovulation induction. The frequency of OHSS has increased with the introduction of menotrophins used for controlled ovarian stimulation in assisted reproductive technologies (ART) as an active strategy for the management of different causes of infertility. With the introduction of gonadotrophin-releasing hormone (GnRH) agonists and the use of higher doses of menotrophins to retrieve a higher number of mature oocytes to maximize ART pregnancy rates, the incidence of severe OHSS has been increased. After in-vitro fertilization (IVF) and embryo transfer, the overall
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