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Human Reproduction, Vol. 14, No. 12, 2930-2931, December 1999
© 1999 European Society of Human Reproduction and Embryology

Debates

Severe OHSS: An `epidemic' of severe OHSS: a price we have to pay?

Michael A. Graf1 and Robert Fischer2,3

1 Endokrinologische Praxisgemeinschaft Hamburg, IVF unit, Lornsenstr. 6, D-22767 Hamburg, and 2 Fertility Center Hamburg, Speersort 4, D-20095 Hamburg, Germany

We read with interest the article on severe ovarian hyperstimulation syndrome (OHSS) and fully agree with the authors (Abramov et al., 1999Go) that overuse of high dose gonadotrophin stimulation protocols, i.e. of those practising pituitary suppression with gonadotrophin-releasing hormone (GnRH) analogues has led to a rise in moderate and severe OHSS, and that a more liberal use of ovulation induction regimes and an increased use in extracorporeal . . . [Full Text of this Article]

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