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Human Reproduction, Vol. 16, No. 9, 2027-2028, September 2001
© 2001 European Society of Human Reproduction and Embryology

Letters to the editor

Is the observed association between increasing paternal age and delayed conception an artefact?

Markku Sallmén1,3 and Ritva Luukkonen2

1 Division of Epidemiology and Social Sciences and 2 Division of Biostatistics, Department of Epidemiology and Biostatistics, Finnish Institute of Occupational Health, Helsinki, Finland

Dear Sir,

The assessment of factors influencing human fertility is an important field of research (Carlsen et al.1992Go; Bonde, 1999Go). The effects of age, in particular, are of interest in assessing the prognosis for infertile couples. Also, age should be adequately taken into account in any studies aiming to find out the risk factors for reduced fertility. We have read with interest the recent paper by Ford and co-workers (2000) in this journal (Ford et al.2000Go). They conducted a cross-sectional study with retrospective data on time to conception (TTC), and observed a strong association between increasing paternal age and delayed conception. In that study, all the mothers and their partners living in the area administered by the Avon Health Authority and with expected delivery date within a 21 month calendar period were invited to enrol in the study. Information on TTC and on related factors . . . [Full Text of this Article]

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