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Human Reproduction, Vol. 17, No. 1, 247-248, January 2002
© 2002 European Society of Human Reproduction and Embryology


Letters to the Editor

Monozygotic twinning: is it related to apoptosis in the embryo?

Yves J.R. Ménézo,1 and Denny Sakkas

Institut Rhonalpin, Laboratoire Marcel Mérieux, 1 Rue Laborde, 69500 BRON, France

Dear Sir,

The advent of prolonged in-vitro preimplantation embryo culture using sequential culture media (Gardner et al., 1998Go) has permitted many IVF laboratories to successfully adopt blastocyst transfer. Unfortunately, an unexpected side effect of this success has seen a small but significant appearance of monozygotic twinning. This has now been described by several authors (Peramo et al., 1999Go; Behr et al., 2000Go; Van Langendonckt et al., 2000Go; da Costa et al., 2001Go; Sheiner . . . [Full Text of this Article]

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