Human Reproduction, Vol. 17, No. 1, 247-248,
January 2002
© 2002 European Society of Human Reproduction and Embryology
Letters to the Editor |
Monozygotic twinning: is it related to apoptosis in the embryo?
Institut Rhonalpin, Laboratoire Marcel Mérieux, 1 Rue Laborde, 69500 BRON, France
Dear Sir,
The advent of prolonged in-vitro preimplantation embryo culture using sequential culture media (Gardner et al., 1998
) has permitted many IVF laboratories to successfully adopt blastocyst transfer. Unfortunately, an unexpected side effect of this success has seen a small but significant appearance of monozygotic twinning. This has now been described by several authors (Peramo et al., 1999
; Behr et al., 2000
; Van Langendonckt et al., 2000
; da Costa et al., 2001
; Sheiner
Notes
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