Human Reproduction, Vol. 18, No. 1, 1-3,
January 2003
© 2003 European Society of Human Reproduction and Embryology
Editorial |
Time to reflect on the Womens Health Initiative (WHI) Study
Editor-in-Chief
| The first 150 words of the full text of this article appear below. |
With 25 years experience of the field of reproductive medicine I can think of no time in my career that hormone replacement therapy (HRT) has been free of controversy. At times the HRT debate has been overshadowed by other issues in the reproductive medicine field, usually in association with developments in assisted reproduction, but throughout my career I have noted unusual polarization of opinion concerning HRT. It is a field of therapeutics on which the views can transcend the usual basis on which we judge medicines. Most medicines are judged on the basis of the best objective data and their clinical role determined by that evidence without emotion coming into play. With HRT, however, there appears to be, for many, an almost partisan support or opposition to HRT.
In the late 1970s working in the menopause clinic at Glasgow Western Infirmary in the adjacent bay to a cardiovascular clinic, the
![]()
CiteULike
Connotea
Del.icio.us What's this?
This article has been cited by other articles:
![]() |
V. Keros, S. Xella, K. Hultenby, K. Pettersson, M. Sheikhi, A. Volpe, J. Hreinsson, and O. Hovatta Vitrification versus controlled-rate freezing in cryopreservation of human ovarian tissue Hum. Reprod., July 1, 2009; 24(7): 1670 - 1683. [Abstract] [Full Text] [PDF] |
||||
![]() |
D. Ferrara, N. Hallmark, H. Scott, R. Brown, C. McKinnell, I. K. Mahood, and R. M. Sharpe Acute and Long-Term Effects of in Utero Exposure of Rats to Di(n-Butyl) Phthalate on Testicular Germ Cell Development and Proliferation Endocrinology, November 1, 2006; 147(11): 5352 - 5362. [Abstract] [Full Text] [PDF] |
||||
![]() |
R. M. Sharpe Perinatal Determinants of Adult Testis Size and Function. J. Clin. Endocrinol. Metab., July 1, 2006; 91(7): 2503 - 2505. [Full Text] [PDF] |
||||
![]() |
M. C. Leal and L. R. Franca The Seminiferous Epithelium Cycle Length in the Black Tufted-Ear Marmoset (Callithrix penicillata) Is Similar to Humans Biol Reprod, April 1, 2006; 74(4): 616 - 624. [Abstract] [Full Text] [PDF] |
||||
![]() |
V. Keros, B. Rosenlund, K. Hultenby, L. Aghajanova, L. Levkov, and O. Hovatta Optimizing cryopreservation of human testicular tissue: comparison of protocols with glycerol, propanediol and dimethylsulphoxide as cryoprotectants Hum. Reprod., June 1, 2005; 20(6): 1676 - 1687. [Abstract] [Full Text] [PDF] |
||||
![]() |
I. Ponjaert-Kristoffersen, T. Tjus, J. Nekkebroeck, J. Squires, D. Verte, M. Heimann, M. Bonduelle, G. Palermo, U.-B. Wennerholm, and on behalf of the Collaborative study of Brussels, Psychological follow-up study of 5-year-old ICSI children Hum. Reprod., December 1, 2004; 19(12): 2791 - 2797. [Abstract] [Full Text] [PDF] |
||||
![]() |
L.E. Bath, G. Tydeman, H.O.D. Critchley, R.A. Anderson, D.T. Baird, and W.H.B. Wallace Spontaneous conception in a young woman who had ovarian cortical tissue cryopreserved before chemotherapy and radiotherapy for a Ewing's sarcoma of the pelvis: Case report Hum. Reprod., November 1, 2004; 19(11): 2569 - 2572. [Abstract] [Full Text] [PDF] |
||||
![]() |
W. H. Wallace and T. W. Kelsey Ovarian reserve and reproductive age may be determined from measurement of ovarian volume by transvaginal sonography Hum. Reprod., July 1, 2004; 19(7): 1612 - 1617. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. Neves-e-Castro Menopause in crisis post-Women's Health Initiative? A view based on personal clinical experience Hum. Reprod., December 1, 2003; 18(12): 2512 - 2518. [Abstract] [Full Text] [PDF] |
||||
![]() |
G. Ena and S. Rozenberg Issues to debate on the Women's Health Initiative (WHI) study. Prescription attitudes among Belgian gynaecologists after premature discontinuation of the WHI study Hum. Reprod., November 1, 2003; 18(11): 2245 - 2248. [Abstract] [Full Text] [PDF] |
||||
![]() |
T. Luukkainen Issues to debate on the Women's Health Initiative study: Failure of estrogen plus progestin therapy for prevention of breast cancer risk Hum. Reprod., August 1, 2003; 18(8): 1559 - 1561. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. Bodis, M. Koppan, J. Garai, K. Zambo, and A. Torok Issues to debate on the Women's Health Initiative: Estrogen: an instrument or the conductor of the orchestra? Hum. Reprod., August 1, 2003; 18(8): 1561 - 1563. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. Bellver, E. Escudero, and A. Pellicer Bilateral partial oophorectomy in the management of severe ovarian hyperstimulation syndrome (OHSS): Ovarian mutilating surgery is not an option in the management of severe OHSS Hum. Reprod., July 1, 2003; 18(7): 1363 - 1367. [Abstract] [Full Text] [PDF] |
||||



