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Human Reproduction, Vol. 18, No. 12, 2495-2496, December 2003
© 2003 European Society of Human Reproduction and Embryology

Editorial

Clinical as well as statistical knowledge is needed when determining how subfertility trials are analysed

Richard P. Dickey1

The Fertility Institute of New Orleans, New Orleans, LA and Section of Reproductive Endocrinology, Department of Obstetrics and Gynecology, Louisiana State University School of Medicine, New Orleans, LA, USA

1 To whom correspondence should be addressed at: 6020 Bullard Avenue, New Orleans, LA 70128, USA. e-mail: info@fertilityinstitute.com

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In the review of statistical errors in analysis and design of subfertility trials by Vail and Gardener (2003)Go, and in comments regarding this paper, the authors of the review, and both the editor (Barlow, 2003Go) and associate editor (Daya, 2003Go) of Human Reproduction, recommend statistical practices that, whilst they may make analysis more reliable, may unintentionally reduce the clinical significance of any results. As a consequence, important clinical and indeed scientific questions will be either not be answered, or be answered so simplistically as to be of questionable . . . [Full Text of this Article]


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