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Human Reproduction, Vol. 18, No. 12, 2497-2498, December 2003
© 2003 European Society of Human Reproduction and Embryology

Editorial

Reply

S. Daya

Department of Obstetrics and Gynecology, Mcmaster University, 1200 main Street West, hamilton, Ontario, Canada L8N 3Z5. E-mail: dayas@mcmaster.ca

The first 10% of the full text of this article appears below.

Thank you for the opportunity to respond to the letter sent by Dr Dickey (Dickey, 2003Go) in which he included comments on my paper on the pitfalls in the design and analysis of efficacy trials in subfertility (Daya, 2003Go). I have several points to make.

First, it appears that Dr Dickey is confusing the analytical and inferential phases of clinical trials. It is well known that the purpose of a clinical trial on efficacy evaluation is to estimate the true (but unknown) effect of the experimental intervention when compared with the control . . . [Full Text of this Article]


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