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E-mail: vansteirteghama@humanreproduction.co.uk
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In an Opinion paper published this month, nine clinicians from different countries enumerate why they believe ovarian hyperstimulation with GnRH antagonists may have advantages over GnRH agonists: reduction of treatment duration, lower risk for ovarian hyperstimulation and no hypo-estrogenic adverse events since pituitary down-regulation is avoided. Probability of achieving a live birth is similar in both protocols. The authors recommend the GnRH antagonist protocol for predicted normal responders and enumerate
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