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Hum. Reprod. Advance Access published online on May 16, 2008

Human Reproduction, doi:10.1093/humrep/den063
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Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology 2008

Letter to the Editor

Differences in gonadotropin-regulated testicular helicase (GRTH/DDX25) single nucleotide polymorphism between Japanese and Chinese populations

Chon-Hwa Tsai-Morris1,3, Eitetsu Koh2 and Maria L. Dufau1

1 Section on Molecular Endocrinology, Endocrinology and Reproduction Research Branch, Program on Developmental Endocrinology and Genetics, National Institute of Child Health and Human Development, National Institute of Health, Bethesda, MD 20892, USA 2 Department of Urology, Kanazawa University School of Medicine, Ishikawa, Japan

3 Correspondence address. E-mail: morrisch@mail.nih.gov

The first 10% of the full text of this article appears below.

Sir,

We would like to make a comment on the article by Zhoucun et al. (2006)Go published in Human Reproduction, entitled ‘Single nucleotide polymorphisms of the gonadotropin-regulated testicular helicase (GRTH) gene may be associated with the human spermatogenesis impairment’. This specifically relates to the conclusion about their finding that allele T of c.852C -> T polymorphism of the GRTH gene might increase the risk of impaired spermatogenesis in humans. In contrast to their patient group . . . [Full Text of this Article]


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