Hum. Reprod. Advance Access originally published online on June 19, 2009
Human Reproduction 2009 24(9):2383-2384; doi:10.1093/humrep/dep217
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© The Author 2009. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org
Letters to the editor |
Reply: Influence of activating and inhibiting killer immunoglobulin-like receptors on predisposition to recurrent miscarriages
Department of Medical Genetics, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Raebareli Road, Lucknow (U.P) 226014, India
1 Correspondence address. Tel: 091-522 -2668004-8 Ext 2338, 2346, 2347, 2339; Fax: 091-522 -26680973/26680017; Email: suraksha@sgpgi.ac.in, sur_ksha_agrawal@yahoo.co.in
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Sir,
We thank Moffett and Hiby for their interest in our paper entitled Influence of activating and inhibiting killer immunoglobulin-like receptors on predisposition to recurrent miscarriages. We share their concern regarding the association of KIRs in recurrent miscarriages in the light of existing confusions and conflicting reports. We undertook this study while being fully aware of the various reports published prior to this one concerning this issue and that there has not been a clear consensus established to date regarding the role of KIRs in the feto-maternal interactions and as predisposing factors to recurrent miscarriage (RM).
In the introduction