Human Reproduction, Vol. 17, No. 1, 250-251,
January 2002
© 2002 European Society of Human Reproduction and Embryology
Letters to the Editor |
Estimation of spontaneous pregnancies in patients after unsuccessful ICSI treatment
IVF & Fertility Laboratory Bikur Cholim Hospital, 5 Strauss Street Jerusalem 91004, Israel
Correspondence: E-mail: almagors{at}hotmail.com
Dear Sir,
We appreciate the interest of Dr Osmanagaoglu and colleagues in our report (Almagoret al., 2001
). Their comments bring up the question of accurate estimation of spontaneous pregnancy rates in couples with severe oligoasthenozoospermia.
We agree with their suggestion that the true rates of spontaneous pregnancy in severe male infertility ought to be determined in couples that are not being treated by assisted reproduction modalities. However, for obvious reasons, such a study group is not likely to be attainable.
Our intention was to assess the rate of spontaneous pregnancies in couples with severe oligoasthenozoospermia who underwent ICSI treatments. We assumed that the chance achieve a spontaneous pregnancy is not influenced by the outcome of ICSI. Therefore, all the study participants were included in the calculation of spontaneous pregnancy rates. assumption is supported by the fact that the spontaneous pregnancy group included both ICSI-successful and unsuccessful couples. Further investigations of larger groups for longer periods of follow-up may clarify whether or not ICSI therapy affects the occurrence of spontaneous pregnancies in couples with severe oligoasthenozoospermia.
Reference
Almagor, M., Dan-Goor, M., Hovav, Y., Yaffe, H. (2001) Spontaneous pregnancies in severe oligoasthenozoospermia. Hum. Reprod., 16, 17801781.
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