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Human Reproduction, Vol. 19, No. 1, 218, January 2004
© 2004 European Society of Human Reproduction and Embryology

Reply: recombinant FSH in alternative doses or versus urinary gonadotrophins for ovulation induction in subfertility associated with polycystic ovary syndrome

M. van Wely1, N. Bayram and F. van der Veen

Center for Reproductive Medicine, Obstetrics and Gynaecology, H4-205, Academic Medical Center, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands

1 To whom correspondence should be addressed. e-mail: m.vanwely{at}amc.uva.nl

Dear Sir,

We would like to thank Dr Lass for pointing out a possibly confusing element in our manuscript (van Wely et al., 2003Go). Although the title of the manuscript states that we compared recombinant FSH (rFSH) with urinary gonadotrophins, in the manuscript we only describe the comparison of rFSH versus urinary FSH (uFSH). Still, the purpose of our Cochrane Review had been to compare rFSH both with uFSH and with HMG. We only analysed and presented results on the comparison of rFSH versus uFSH because there are, at the moment, no studies comparing rFSH with HMG in ovulation induction in women with polycystic ovary syndrome, as Dr Lass rightly states. In the next update of our Cochrane review in the Cochrane library we will state clearly the eligible comparisons.

References

vanWely M, Bayram N and van der Veen F (2003) Recombinant FSH in alternative doses or versus urinary gonadotrophins for ovulation induction in subfertility associated with polycystic ovary syndrome: a systematic review based on a Cochrane review. Hum Reprod 18,1143–1149.[Abstract/Free Full Text]


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