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Hum. Reprod. Advance Access originally published online on October 18, 2007
Human Reproduction 2007 22(12):3263; doi:10.1093/humrep/dem329
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© The Author 2007. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Letters to the Editor

Episodic air pollution is associated with increased DNA fragmentation in human sperm without other changes in semen quality

Mina Jafarabadi

Reproductive Health Research Center, Tehran University of Medical Sciences, Tehran, Iran

Correspondence address. E-mail: jafarabadi{at}sina.tums.ac.ir

Episodic air pollution is associated with increased DNA fragmentation in human sperm without other changes in semen quality

Sir,

In the Method section of their article Rubes et al. (2005)Go mentioned ‘To capture exposures to episodes of high air pollution, men were sampled monthly during the winter of 1996, ... followed by ... a fourth winter sample in February 1997’. The question is: considering the fact that spermatogenesis in human takes 72–90 days to be completed, how could the samples taken in the time of peak air pollution provide longitudinal data to examine potential associations of exposure to high air pollution? The semen samples taken in first winter months mostly project the autumn's quality of spermatogenesis, and spermatogenesis in winter seems better to be analysed from spring samples.

References

Rubes J, Selevan SG, Evenson DP, Zudova D, Vozdova M, Zudova Z, Robbins WA, Perreault SD. Episodic air pollution is associated with increased DNA fragmentation in human sperm without other changes in semen quality. Hum Reprod (2005) 20:2776–2783.[Abstract/Free Full Text]


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