Skip Navigation

This Article
Right arrow Full Text (PDF )
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (57)
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Wisanto, A.
Right arrow Articles by Devroey, P.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Wisanto, A.
Right arrow Articles by Devroey, P.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Human Reproduction, Vol. 10, No. 10, pp. 2713-2718, 1995
© 1995 European Society of Human Reproduction and Embryology

research-article

Obstetric outcome of 424 pregnancies after intracytoplasmic sperm injection

A. Wisanto1,3, M. Magnus, M. Bonduelle2, J. Liu, M. Camus, H. Tournaye, I. Liebaers2, A.C.Van Steirteghem and P. Devroey

1Centre for Reproductive Medicine University Hospital, Dutch-speaking Brussels Free University (Vrije Universiteit Brussel) Laarbeeklaan 101, B-1090 Brussels, Belgium 2Centre for Medical Genetics, University Hospital, Dutch-speaking Brussels Free University (Vrije Universiteit Brussel) Laarbeeklaan 101, B-1090 Brussels, Belgium

Correspondence: 3To whom correspondence should be addressed at: Centre for Reproductive Medicine, University Hospital, Dutch-speaking Brussels Free University (Vrije Universiteit Brussel), Laarbeeklaan 101, B-1090 Brussels, Belgium

An evaluation of the outcome of pregnancies resulting from intracytoplasmic sperm injection for severe male factor infertility was conducted by analysing the data obtained from the patients and/or their obstetrician/gynaecologist on standardized questionnaires. The data from 424 pregnancies between April 1991 and September 1994 were analysed. Early pregnancy loss before 16 weeks occurred in 99 cases (23.3%), including 48 clinical abortions (11.3%),47 subclinical pregnancies (11.1%) and four ectopic pregnancies (0.9%). Vanishing twins and triplets, which could be regarded as early embryonic wastage, were found in 36 cases (8.5%). One pregnancy was interrupted at week 15 of gestation because of anhydramnios, and four pregnancies (0.9%) ended in spontaneous late abortions before 26 weeks. A total of 320 pregnancies (75.5%) resulted in the birth of at least one child; 222 of these (69.3%) were singletons, 93 were twins (29.1%) and five were triplets (1.6%). The problems of prematurity and low birthweight were especially related to the multiplicity of pregnancies. Furthermore, from among the total of 423 babies born, we have observed three cases of stillbirth and five cases of neonatal mortality. The perinatal mortality rate was therefore 18.9 per 1000 births. The results of this study show that the obstetric outcome of these pregnancies was similar to that obtained after conventional in-vitro fertilization and other assisted reproduction techniques.

Key words: intracytoplasmic sperm injection/outcome/pregnancy

1Present address: Unit of Reproductive Medicine, Virga Jesse Hospital, Stadsomvaart 11, 3500 Hasselt, Belgium


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Hum ReprodHome page
Y.A. Wang, D. Healy, D. Black, and E.A. Sullivan
Age-specific success rate for women undertaking their first assisted reproduction technology treatment using their own oocytes in Australia, 2002-2005
Hum. Reprod., July 1, 2008; 23(7): 1633 - 1638.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
M. Bahceci and U. Ulug
Does underlying infertility aetiology impact on first trimester miscarriage rate following ICSI? A preliminary report from 1244 singleton gestations
Hum. Reprod., March 1, 2005; 20(3): 717 - 721.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
P. J. Boerrigter, J. J. de Bie, B. M.J.L. Mannaerts, B. P. van Leeuwen, and D. P.J. Passier-Timmermans
Obstetrical and neonatal outcome after controlled ovarian stimulation for IVF using the GnRH antagonist ganirelix
Hum. Reprod., August 1, 2002; 17(8): 2027 - 2034.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
M. Bonduelle, I. Liebaers, V. Deketelaere, M.-P. Derde, M. Camus, P. Devroey, and A. Van Steirteghem
Neonatal data on a cohort of 2889 infants born after ICSI (1991-1999) and of 2995 infants born after IVF (1983-1999)
Hum. Reprod., March 1, 2002; 17(3): 671 - 694.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
N. Greenwold and E. Jauniaux
Collection of villous tissue under ultrasound guidance to improve the cytogenetic study of early pregnancy failure
Hum. Reprod., February 1, 2002; 17(2): 452 - 456.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
ESHRE PGD Consortium Steering Committee
ESHRE Preimplantation Genetic Diagnosis (PGD) Consortium: data collection II (May 2000)
Hum. Reprod., December 1, 2000; 15(12): 2673 - 2683.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
S. Nuojua-Huttunen, M. Gissler, H. Martikainen, and L. Tuomivaara
Obstetric and perinatal outcome of pregnancies after intrauterine insemination
Hum. Reprod., August 1, 1999; 14(8): 2110 - 2115.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
A. Loft, K. Petersen, K. Erb, A.L. Mikkelsen, J. Grinsted, F. Hald, J. Hindkjar, K.M. Nielsen, P. Lundstrom, A. Gabrielsen, et al.
A Danish national cohort of 730 infants born after intracytoplasmic sperm injection (ICSI) 1994–1997
Hum. Reprod., August 1, 1999; 14(8): 2143 - 2148.
[Abstract] [Full Text] [PDF]

Home page
 JAMAHome page
G. D. Palermo, L. T. Colombero, G. L. Schattman, O. K. Davis, and Z. Rosenwaks
Evolution of Pregnancies and Initial Follow-up of Newborns Delivered After Intracytoplasmic Sperm Injection
JAMA, December 18, 1996; 276(23): 1893 - 1897.
[Abstract] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.