Skip Navigation

This Article
Right arrow Full Text (PDF )
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (30)
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Fahy, U. M.
Right arrow Articles by Hull, M. G.R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Fahy, U. M.
Right arrow Articles by Hull, M. G.R.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Human Reproduction, Vol. 10, No. 3, pp. 572-575, 1995
© 1995 European Society of Human Reproduction and Embryology

research-article

Infertility: In-vitro fertilization in completely natural cycles*

Una M. Fahy1, David J. Cahill, Peter G. Wardle and Michael G.R. Hull

Reproductive Medicine Unit, Department of Obstetrics and Gynaecology, University of Bristol, St Michael's Hospital Bristol BS2 8EG, UK

Correspondence: 1To whom correspondence should be addressed at: Department of Obstetrics and Gynaecology, Leicester Royal Infirmary NHS Trust, Infirmary Square, Leicester LEI 5WW, UK

Our objective was to assess the efficacy of in-vitro fertilization (IVF) in natural ovarian cycles in couples with tubal and unexplained infertility. A prospective study design was used. A total of 39 fully investigated couples, who were patients at the Reproductive Medicine Unit, St Michael's Hospital, Bristol, UK, took part; they were diagnosed with either tubal disease (n = 26) or unexplained infertility (n = 13). Procedures involved daily capillary blood sampling, daily vaginal ultrasonography and vaginal oocyte recovery under sedation at mid-cycle. The main outcome measures were fertilization, implantation and pregnancy rates. Although more of the women with tubal disease were parous, there were no other significant differences between the two groups. The 39 couples with infertility of tubal or unexplained aetiology had 79 cycles of IVF in otherwise completely natural cycles. The overall fertilization rate was 80% and the implantation rate was 14.0%. A trend was observed for higher success rates in women with tubal disease. We conclude that natural cycle IVF and embryo transfer offers an acceptable chance of pregnancy and an opportunity for the in-depth investigation of follicular and ovarian function in couples with defined causes of infertility. The possibly lower success rate in women with unexplained infertility warrants further study of follicular function and endocrinology.

Key words: implantation rates/natural cycle IVF/pregnancy rates/transvaginal oocyte recovery

*Presented at the Ninth Annual Meeting of ESHRE, Thessaloniki, Greece, June 27-30, 1990


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Hum Reprod UpdateHome page
W. Ombelet, P. De Sutter, J. Van der Elst, and G. Martens
Multiple gestation and infertility treatment: registration, reflection and reaction--the Belgian project
Hum. Reprod. Update, January 1, 2005; 11(1): 3 - 14.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
H. J. Ingerslev, A. Hojgaard, J. Hindkjar, and U. Kesmodel
A randomized study comparing IVF in the unstimulated cycle with IVF following clomiphene citrate
Hum. Reprod., April 1, 2001; 16(4): 696 - 702.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
P. Puttemans, R. Campo, S. Gordts, and I. Brosens
Hydrosalpinx and ART: Hydrosalpinx - functional surgery or salpingectomy?
Hum. Reprod., July 1, 2000; 15(7): 1427 - 1430.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
R.M.J. Janssens, C.B. Lambalk, J.P.W. Vermeiden, R. Schats, and J. Schoemaker
In-vitro fertilization in a spontaneous cycle: easy, cheap and realistic
Hum. Reprod., February 1, 2000; 15(2): 314 - 318.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
S. Bassil, P.A. Godin, and J. Donnez
Outcome of in-vitro fertilization through natural cycles in poor responders
Hum. Reprod., May 1, 1999; 14(5): 1262 - 1265.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.