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Human Reproduction, Vol. 10, No. 7, pp. 1795-1796, 1995
© 1995 European Society of Human Reproduction and Embryology


research-article

Recurrence of fibroids after myomectomy: a transvaginal ultrasonographic study

L. Fedele1, F. Parazzini1,2,4, L. Luchini2,3, R. Mezzopane2, L. Tozzi1 and L. Villa1

1Clinica Ostetrico Ginecologica ‘Luigi Mangiagalli’, Universitá di Milano via Commenda 12, 20100 Milano 2Istituto di Ricerche Farmacologiche ‘Mario Negri’ via Eritrea 62, 20157 Milano 3Istituto Europeo di Oncologia via Ripamonti 332/10, 20141 Milano, Italy

Correspondence: 4To whom correspondence should be addressed at Istituto di Ricerche Farmacologiche

Frequency of recurrence of fibroids after myomectomy has been evaluated in 145 women (median age 38 years, range 21–52) who underwent myomectomy. After surgery all women returned for follow-up visit every 12 months after surgery. Transvaginal ultrasound examination was performed routinely in every patient at 24 and 60 months and at 12, 36 and 48 months if there were any abnormal pelvic findings or suspicious symptomatology. A total of 39 (27%) women gave birth after myomectomy. For the whole series, the cumulative probability of recurrence (CPR) increased constantly during the study period reaching 51% in 5 years. The 5-year CPR decreased with parity after myomectomy, being 55% for women with no childbirth after surgery and 42% (based on 13 recurrences, P < 0.01) for those who gave birth.

Key words: myomectomy/recurrence/uterine fibroids


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