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Human Reproduction, Vol. 11, No. 3, pp. 518-522, 1996
© 1996 European Society of Human Reproduction and Embryology

Fertility after laparoscopic myomectomy of large intramural myomas: preliminary results

Jean-Bernard Dubuisson1, Charles Chapron, Xavier Chavet and Stelios S. Gregorakis

Service de Chirurgie Gynecologique, Clinique Universitaire Baudelocque CHU Cochin Port-Royal, 123 Boulevard Port-Royal, 75014 Paris, France

Correspondence: 1To whom correspondence should be addressed

Fertility outcome following laparoscopic myomectomy was evaluated. A prospective clinical study was carried out between October 1990 and October 1993 in 21 infertile patients who underwent laparoscopic myomectomy for a myoma measuring 3>;5 cm in diameter. The overall rate of intrauterine pregnancy was 333% (seven patients). Out of 12 patients with infertility factors associated with uterine myomas, three (25.0%) became pregnant, whereas four (44.4%) out of nine patients with no other associated infertility factor became pregnant. No uterine rupture was observed. Out of the seven pregnancies, four were spontaneous and began within 1 year of the operation. The other three were achieved after in-vitro fertilization in patients with associated infertility factors. In the four patients who gave birth by Caesarean section, no adhesions were found on the myomectomy scar. From these preliminary results, laparoscopic surgery for myomas seems to offer comparable results with those obtained by laparotomy.

Key words: infertility/laparoscopic myomectomy/myomas

Submitted on July 14, 1995; accepted on December 12, 1995.


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