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Human Reproduction, Vol. 12, No. 11, pp. 2370-2372, 1997
© 1997 European Society of Human Reproduction and Embryology

Case Report: Unilateral oophorectomy in polycystic ovary syndrome: a treatment option in highly selected cases?

Eugenie M. Kaaijk1,2,3, Johan F. Beek2, Johan V.T.H. Hamerlynck1 and Fulco van der Veen1

1 Centre for Reproductive Medicine PO Box 22700, 1100 DE Amsterdam, The Netherlands 2 Laser Centre, Academic Medical Centre PO Box 22700, 1100 DE Amsterdam, The Netherlands

Correspondence: 3To whom correspondence should be addressed

We performed unilateral oophorectomy (UO) in three patients with polycystic ovary syndrome (PCOS) and longstanding infertility. The indication for performing this procedure was a combination of ovarian pathology and the long-standing infertility. All three patients were resistant to clomiphene citrate and before UO all patients had been treated unsuccessfully with gonadotrophins and in-vitro fertilization. All three patients became ovulatory within the first month after UO. Two patients conceived 11 and 12 months after surgery respectively and delivered healthy babies. Testosterone concentrations decreased in two patients to upper values of the normal range and remained unchanged in one patient. We conclude that restoration of ovulation can be a beneficial side-effect of UO in clomiphene citrate resistant patients with PCOS and long-standing infertility.

Key words: androgens/ovarian pathology/ovulation/pregnancy/surgery

Submitted on March 24, 1997; accepted on August 19, 1997.


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E. M. Kaaijk, J. V.T.H. Hamerlynck, J. F. Beek, and F. van der Veen
Clinical outcome after unilateral oophorectomy in patients with polycystic ovary syndrome
Hum. Reprod., April 1, 1999; 14(4): 889 - 892.
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