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Human Reproduction, Vol. 14, No. 11, 2917-2920, November 1999
© 1999 European Society of Human Reproduction and Embryology

Human live birth and sperm–sex ratios compared

J. Graffelman1,3, E.F. Fugger2, K. Keyvanfar2 and J.D. Schulman2

1 University Pompeu Fabra, Department of Economics, Barcelona, Spain and 2 Genetics & IVF Institute, 3020 Javier Road, Fairfax, VA 22031, USA

The human secondary sex ratio is compared with the percentage of Y-chromosome bearing spermatozoa in human semen. Live birth sex ratio is about 51.3%, whereas the overall percentage of Y-chromosome bearing spermatozoa in our study samples was 50.3%, i.e. 1% closer to the proportion expected by Mendelian segregation. The observed difference between live birth and sperm–sex ratios was significant (P < 0.0001). A possible effect of male age on the percentage Y-bearing spermatozoa was found to be non-significant.

Key words: fluorescence in-situ hybridization/secondary sex ratio/sperm–sex ratio

3 To whom correspondence should be addressed at: University Pampeu Fabra, Ramon Trias Fargas 25–27, 08005 Barcelona, Spain


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