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Human Reproduction, Vol. 14, No. 12, 2938-2940, December 1999
© 1999 European Society of Human Reproduction and Embryology

Opinions

Cryopreservation of the human female gamete: current and future issues

Debra A. Gook1 and David H. Edgar

Reproductive Biology Unit, Royal Women's Hospital, Carlton, Victoria 3053, Australia

The potential advantages associated with the ability to freeze and store human oocytes successfully have been well established for some time. Not only would it allow the circumvention of moral, ethical and legal problems which arise as an inevitable consequence of embryo freezing, but also it would offer the prospect of broadening the fertility options available to women who, for a variety of medical reasons, are likely to lose ovarian function prematurely. Banks of frozen donated oocytes would facilitate the donation process, which is often complicated by a requirement for donor–recipient synchrony. More controversially, oocyte storage would also open the door to the possibility of women, with no medical indications and no immediate plans to conceive, being able to store `young eggs' for potential use at a later date.

Technically, the possibility of offering oocyte cryopreservation as a routine procedure had seemed somewhat remote after failure to reproduce early reports . . . [Full Text of this Article]

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