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Human Reproduction, Vol. 14, No. 7, 1707-1709, July 1999
© 1999 European Society of Human Reproduction and Embryology

Severe ovarian hyperstimulation syndrome following salvage of empty follicle syndrome: Case report

I.O. Evbuomwan1, J.D. Fenwick, R. Shiels, M. Herbert and A.P. Murdoch

Centre for Reproductive Medicine, RVI Trust, Newcastle upon Tyne, NE1 4LP, UK

We report a case of severe ovarian hyperstimulation syndrome (OHSS) following a rescue of empty follicle syndrome (EFS). This suggests that the risk of developing OHSS remains unaltered even in the presence of EFS. The case supports the possibility of obtaining oocytes that fertilize and cleave normally after a second dose of human chorionic gonadotrophin (HCG) and a repeat oocyte retrieval. It supports the suggestion that the follicles are not necessarily empty in EFS. It demonstrates further that OHSS cannot be prevented by aspiration of follicular fluid and patients with large numbers of follicles and EFS must be warned of this potential complication.

Key words: EFS/gonadotrophins/ICSI/ovarian hyperstimulation

1 To whom correspondence should be addressed


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