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Human Reproduction, Vol. 15, No. 10, 2152-2153, October 2000
© 2000 European Society of Human Reproduction and Embryology

Case Report

Successful pregnancy and birth after IVF in a woman with cystic fibrosis: Case Report

Helen C. Rodgers1, Alan J. Knox1, Philip J. Toplis2 and Simon J. Thornton3,4

1 Respiratory Medicine Unit, City Hospital, Hucknall Road, Nottingham NG5 1PB, 2 Obstetrics and Gynaecology Unit, Frimley Park Hospital, Camberley, Surrey GU16 5UJ and 3 Centres for Assisted Reproduction, The Park Hospital, Arnold, Nottingham NG5 8RX, UK

As survival increases, patients with cystic fibrosis (CF) are often confronted with reproductive issues. Initial reports gave conflicting advice regarding the outcome of pregnancy in CF. However a recent large longitudinal study of pregnancies in CF women suggested that pregnancy has little impact on morbidity or mortality. Reduced fertility in CF women has been described, possibly due to thickened cervical mucus, and intrauterine insemination (IUI) has been used to overcome this. We report the first woman with CF, to our knowledge, to be successfully treated with IVF after repeated failed attempts at IUI.

Key words: cystic fibrosis/fertility/IVF

4 To whom correspondence should be addressed at: Centres for Assisted Reproduction, The Park Hospital, Arnold, Nottingham NG5 8RX, UK. E-mail: info{at}care-ivf.com


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