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Human Reproduction, Vol. 15, No. 11, 2447, November 2000
© 2000 European Society of Human Reproduction and Embryology

Letters to the editor

HLA-DR4 and pre-eclampsia

D.C. Kilpatrick

Blood Transfusion Service Laboratories, 2 Foreest Road, Edinburgh EH1 2QN, UK

Dear Sir,

Takukuwa et al. (1999) recently reported HLA-DR data from a group of Japanese pre-eclampsia patients. The finding that was emphasized was a higher frequency of DR ß1*04 genotypes in the small sub-group of patients positive for anti-cardiolipin antibodies (ACA) compared to normal fertile women. Nevertheless, a similar trend is apparent with ACA-negative patients, and the . . . [Full Text of this Article]

References

Koichi Takakuwa

Department of Obstetrics and Gynecology, Niigata University School of Medicine, 1-757 Asahimachi-dori, Niigata 951-8510, Japan


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