Human Reproduction, Vol. 15, No. 2, 493-495,
February 2000
© 2000 European Society of Human Reproduction and Embryology
Letters to the Editor |
A comparison of three GnRH analogues in an IVF programme
IVF Unit, Department of Obstetrics and Gynecology, Kaplan Medical Center, Rehovot Hadassah-Hebrew University School of Medicine, Jerusalem, Israel
Dear Sir,
We read with interest the paper by Dada et al. (1999) on the comparison of three different gonadotrophin-releasing hormone (GnRH) analogues for pituitary desensitization prior to ovarian stimulation for in-vitro fertilization (IVF). The authors have found that with intranasal nafarelin and depot leuprorelin pituitary desensitization and ovarian suppression are obtained significantly earlier as compared with s.c. buserelin administration. The three preparations were found comparable in every other aspect of ovarian response to stimulation and cycle outcome.
In its conventional packaging, nafarelin (Synarel) is metered to give 200 µg per
References
Assisted Conception Unit, St James University Hospital, Beckett Street, Leeds LS9 7TF, UK