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Human Reproduction, Vol. 15, No. 5, 1173-1177, May 2000
© 2000 European Society of Human Reproduction and Embryology

Fertility outcome after ectopic pregnancy and use of an intrauterine device at the time of the index ectopic pregnancy

A. Bernoux1, N. Job-Spira1, E. Germain2, J. Coste1 and J. Bouyer1,3

1 INSERM U292, Hôpital de Bicêtre, 82 rue du Général Leclerc, 94276 Le Kremlin-Bicêtre Cedex and 2 Centre Hospitalier Hôtel-Dieu, Service Epidémiologie, Prévention et Economie de la Santé, Clermont-Ferrand, France

Fertility after ectopic pregnancy (EP) was investigated in a non-selected population taking into account intrauterine device (IUD) use at the time of the EP. Between January 1992 and June 1996, 647 women listed in the EP register of Auvergne (France) were followed up. The analysis included only the 328 women who were seeking to become pregnant: 23 women using IUD at the time of the index EP (IUD users) and 305 IUD non-users. Among IUD users, there was no recurrence of EP, and the 1 year cumulative rate was 87% [95% confidence interval (CI): 73–100%] for intrauterine pregnancies and 86% (95% CI: 72–100%) for deliveries. Among IUD non-users, the 2 year cumulative rate for recurrence of EP was 28% (95% CI: 17–39%), and the 1 year cumulative rates were 60% (95% CI: 53–66%) for intrauterine pregnancies and 44% (95% CI: 38–56%) for deliveries. The adjusted intrauterine pregnancy rate of IUD users was not significantly different from that of IUD non-users. However, IUD non-users had more miscarriages, so their delivery rate was lower.

Key words: ectopic pregnancy/epidemiology/fertility/intrauterine device/prospective study

3 To whom correspondence should be addressed


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