Skip Navigation

This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF ) Freely available
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (11)
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Yazawa, H.
Right arrow Articles by Nakada, T.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Yazawa, H.
Right arrow Articles by Nakada, T.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Human Reproduction, Vol. 15, No. 9, 1917-1920, September 2000
© 2000 European Society of Human Reproduction and Embryology

Apoptosis of testicular germ cells induced by exogenous glucocorticoid in rats

H. Yazawa, I. Sasagawa1 and T. Nakada

Department of Urology, Yamagata University School of Medicine, 2-2-2 Iidanishi, Yamagata 990-9585, Japan

The influence of exogenous glucocorticoid, dexamethasone (Dex), on testicular germ cell apoptosis was investigated in rats. The percentages of apoptotic tubules and apoptotic germ cells in the Dex-treated group of rats were about seven-fold and 10-fold higher respectively than in either the control group, or in rats treated with glucocorticoid receptor agonist (GR-A), or in rats treated with both Dex and GR-A. These results suggest that, in rats, apoptosis of testicular germ cells is mediated by glucocorticoid receptors.

Key words: apoptosis/germ cell/glucocorticoid/rat

1 To whom correspondence should be addressed at: Department of Urology, Yamagata University, School of Medicine, 2-2-2 Iidanishi, Yamagata-shi, Yamagata 990-9585, Japan.E-mail: isasaga{at}med.id.yamagata-u.ac.jp


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 ReproductionHome page
A Wagner and R Claus
Involvement of glucocorticoids in testicular involution after active immunization of boars against GnRH
Reproduction, February 1, 2004; 127(2): 275 - 283.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.