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Human Reproduction, Vol. 16, No. 12, 2578-2582, December 2001
© 2001 European Society of Human Reproduction and Embryology

Transvaginal ultrasound-guided embryo transfer improves pregnancy and implantation rates after IVF

Kayoko Kojima1,3, Mari Nomiyama1, Takumi Kumamoto1, Yumi Matsumoto1 and Tsuyoshi Iwasaka2

1 Reproductive Centre, Takagi Hospital, 141-11 Sakemi, Ookawa 831-0016 and 2 Department of Obstetrics and Gynecology, Saga Medical School, 5-1-1 Nabeshima, Saga 849-8501, Japan

BACKGROUND: Attempts are constantly being made to improve clinical pregnancy rates after IVF and embryo transfer. Since November 1998, we have gradually been adopting transvaginal ultrasound guidance during embryo transfer. We retrospectively examined the efficacy of this method on pregnancy and implantation rates. METHODS: The results of 846 cycles from our IVF–embryo transfer programme were analysed and comparisons were made between those carried out using ultrasound guidance and those by the clinical touch method. RESULTS: Higher pregnancy and implantation rates (28.9 and 15.2% respectively) were found in the group using the transvaginal ultrasound guidance during embryo transfer compared with those in the group using the clinical touch method (13.1 and 7.0% respectively). The differences were statistically significant (P < 0.01). There was no significant difference in ectopic pregnancy rates between the two groups. CONCLUSION: The use of transvaginal ultrasound-guided embryo transfer significantly improved both pregnancy and implantation rates. Although technically difficult, we suggest its use may maximize the chances of achieving a successful pregnancy outcome.

Key words: air bubble/embryo transfer/IVF/pregnancy rate/transvaginal ultrasound guidance

3 To whom correspondence should be addressed. E-mail: ka{at}po.saganet.ne.jp


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