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Human Reproduction, Vol. 17, No. 1, 11-12, January 2002
© 2002 European Society of Human Reproduction and Embryology

OPINION

Preimplantation sex selection for family balancing in India

A. Malpani,1, A. Malpani and D. Modi

Malpani Infertility Clinic, Colaba, Mumbai 400 005, India

Abstract

We describe our experience with the use of embryo biopsy and fluorescent in-situ hybridization (FISH) in order to sex embryos for the purpose of family balancing in a private IVF clinic in India from April 1999–April 2001. Embryos were biopsied and analysed on day 3, cultured in sequential media, and then transferred on day 4 or day 5 after morphological selection of the best embryos. From a total of 42 cycles started, we achieved 14 clinical pregnancies and have had nine live births so far with five ongoing pregnancies. This is the first report of the use of preimplantation sex selection for family balancing in India, where couples place a premium on having baby boys, and the social and ethical aspects of the use of this technology in this setting are discussed.

Key words: blastocyst transfer/embryo biopsy/family balancing/fluorescent in-situ hybridization (FISH)/sex selection

Notes

1 To whom correspondence should be addressed. E-mail: malpani{at}vsnl.com


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