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Human Reproduction, Vol. 17, No. 10, 2621-2625, October 2002
© 2002 European Society of Human Reproduction and Embryology

Impact of patients’ choice for single embryo transfer of a top quality embryo versus double embryo transfer in the first IVF/ICSI cycle

D.De Neubourg1, K. Mangelschots, E. Van Royen, M. Vercruyssen, G. Ryckaert, M. Valkenburg, J. Barudy-Vasquez and J. Gerris

Center for Reproductive Medicine, Middelheim Hospital, Lindendreef 1, 2020 Antwerp, Belgium

BACKGROUND: The aim of this study was to evaluate the impact of transferring a single top quality embryo in the first IVF/ICSI cycle of patients <38 years old who chose to have one or two embryos transferred. METHODS: A total of 262 patients participated in the study, and 243 transfers were performed: 156 (64%) patients chose the transfer of a single top quality embryo, if available, and two non-top quality embryos if not available; 87 (36%) patients chose to have a double embryo transfer regardless of embryo quality. RESULTS: In the first group an ongoing pregnancy rate of 40% (63/156) with a twin pregnancy rate of 2% (1/63) was achieved. In the second group the ongoing pregnancy rate was 44% (38/87) with 26% (10/38) twin pregnancies. In the patient group with only one embryo transferred, irrespective of the patient’s choice, the ongoing pregnancy rate was 43% (54/127) with no twin pregnancies. For the study population as a whole, the ongoing pregnancy rate was 42% (101/243) with 11% (11/101) twins. CONCLUSION: We conclude that the introduction of single embryo transfer in the first IVF/ICSI cycle is highly acceptable in women <38 years old.

Key words: embryo selection/single embryo transfer/twin pregnancy prevention

1 To whom correspondence should be addressed. E-mail: diane.deneubourg{at}ocmw.antwerpen.be


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