Human Reproduction, Vol. 17, No. 2, 521-523,
February 2002
© 2002 European Society of Human Reproduction and Embryology
Letters to the editor |
Myths about endocrine disruption and the male reproductive system should not be propagated
1 Wildlife and Contaminants Program, World Wildlife Fund, 1250 24th Street, NW Washington, DC 20036 and 2 114 Lefevre Hall, Division of Biological Sciences, University of Missouri, Columbia, MO 65211, USA
Dear Sir,
We find the response by Mike Joffe to our article showing that fetal exposure to sub-clinical doses of ethinyl estradiol (EE) alters development of the prostate and testes in male mice perplexing on a number of counts.
First, Joffe challenges the statement we made in the introduction of our paper concerning the proportion of pregnant women who become pregnant while using oral contraceptives. In a recently published guide for physicians concerning the use of oral contraceptives (Dickey, 1998
), the `typical' pregnancy rate for both combination oral contraceptives and progestin-only oral contraceptives is
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