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Human Reproduction, Vol. 17, No. 3, 666-670, March 2002
© 2002 European Society of Human Reproduction and Embryology

The impact of the embryo transfer catheter on the pregnancy rate in IVF

Hans G.I. van Weering1,3, Roel Schats1, Joseph McDonnell2, Jacqueline M. Vink1, Jan P.W. Vermeiden1 and Peter G.A. Hompes1

1 VU University Medical Centre, Department of Obstetrics, Gynaecology and Reproductive Medicine, P.O.Box 7057, 1007 MB Amsterdam and 2 Institute for Medical Technology Assessment, Erasmus University, Rotterdam, The Netherlands

BACKGROUND: The aim was to assess whether the type of embryo transfer set used for embryo transfer affects the ongoing pregnancy rate in IVF. METHODS: The TDT set was compared with the K-soft 5000 in a, large, prospective, randomized study. Patients were randomized moments before transfer by drawing a consecutively numbered, sealed, opaque envelope indicating the catheter to be used. RESULTS: 2059 embryo transfers in 1296 patients were analysed. The ongoing pregnancy rate was significantly higher in the K-soft group. If the first transfer of a patient (n = 1296) within this study period was analysed, the ongoing pregnancy rates were 27.1 versus 20.5% (P = 0.006). If the analysis is limited to patients that underwent their very first transfer ever (n = 607), the ongoing pregnancy rates were 30.3 versus 20.0% (P = 0.003) in favour of the K-soft. CONCLUSION: We conclude from these data that the type of embryo transfer set used for embryo transfer does affect the ongoing pregnancy rate and that the impact of the variable transfer catheter on the ongoing pregnancy rate increases when the a priori chance of pregnancy increases.

Key words: catheter/embryo transfer/IVF/pregnancy rate/transfer procedure

3 To whom correspondence should be addressed. E-mail: h.vanweering{at}vumc.nl

Submitted on March 29, 2001; resubmitted on September 14, 2001


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