Human Reproduction, Vol. 18, No. 10, 2122-2123,
October 2003
© 2003 European Society of Human Reproduction and Embryology
Associate Editor's commentary: Rescue ICSI revisited
MAR&Gen, Molecular Assisted Reproduction and Genetics, Gracia 36, 18002 Granada, Spain. e-mail: cmendoza@ugr.es
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ICSI was first applied in cases of severe male factor infertility in which conventional IVF would be expected to fail or to give poor outcomes (Van Steirteghem et al., 1993
). More recently, however, ICSI has been increasingly used in cases in which conventional IVF would not necessarily be inefficient. In such cases, ICSI is often preferred because of its reliability in terms of achieving high fertilization rates despite the occurrence and severity of different sperm abnormalities, some of which are not detectable by standard semen examinations.