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Human Reproduction, Vol. 18, No. 12, 2719-2720, December 2003
© 2003 European Society of Human Reproduction and Embryology

Clinical evidence for an LH ceiling?

Ernest Loumaye1,5, P. Engrand2, Z. Shoham3, S.G. Hillier4 and D.T. Baird4

1 Department of Gynecology, Cliniques universitaires St Luc, University of Louvain, B-1200 Bruxelles, Belgium, 2 Serono International, Geneva, Switzerland, 3 Department of Obstetrics and Gynecology, Kaplan Medical Center, Rehovot, Israel and 4 University of Edinburgh Centre for Reproductive Biology, Edinburgh, UK

5 To whom correspondence should be addressed. e-mail: ernest.loumaye@wanadoo.fr

The first 10% of the full text of this article appears below.

Dear Sir,

We read with interest the letter by M.Filicori (Filicori et al., 2003Go) commenting on our pilot studies published earlier in Human Reproduction (Loumaye et al., 2003Go).

Filicori et al. remind us that they have repeatedly reported a reduction in ‘small’ follicles (<10 mm) by administering LH activity during the follicular phase. This supports a ‘ceiling’ for LH on antral follicles with a diameter <10 mm; however, they challenge such effect of LH on larger follicles (>10 mm). This is based on four pilot studies published by the same . . . [Full Text of this Article]


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