Human Reproduction, Vol. 18, No. 12, 2719-2720,
December 2003
© 2003 European Society of Human Reproduction and Embryology
Clinical evidence for an LH ceiling?
1 Department of Gynecology, Cliniques universitaires St Luc, University of Louvain, B-1200 Bruxelles, Belgium, 2 Serono International, Geneva, Switzerland, 3 Department of Obstetrics and Gynecology, Kaplan Medical Center, Rehovot, Israel and 4 University of Edinburgh Centre for Reproductive Biology, Edinburgh, UK
5 To whom correspondence should be addressed. e-mail: ernest.loumaye@wanadoo.fr
| The first 10% of the full text of this article appears below. |
Dear Sir,
We read with interest the letter by M.Filicori (Filicori et al., 2003
) commenting on our pilot studies published earlier in Human Reproduction (Loumaye et al., 2003
).
Filicori et al. remind us that they have repeatedly reported a reduction in small follicles (<10 mm) by administering LH activity during the follicular phase. This supports a ceiling for LH on antral follicles with a diameter <10 mm; however, they challenge such effect of LH on larger follicles (>10 mm). This is based on four pilot studies published by the same
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