Human Reproduction, Vol. 18, No. 2, 459,
February 2003
© 2003 European Society of Human Reproduction and Embryology
Origin of sperm with extra chromosome set
1 Department of Obstetrics and Gynecology University of Debrecen, School of Medicine, 98 Nagyerdei krt., H-4012 Debrecen, Hungary and 2 The Sperm Physiology Laboratory, Department of Obstetrics and Gynecology, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06510 USA
3 To whom correspondence should be addressed. e-mail: ja@jaguar.dote.hu
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Dear Sir,
We read with interest the article by Devillard et al. (2002
), in which they report on the high frequency of various polyploidies in large-headed sperm. Examining sperm nuclei by FISH from three patients with macrocephalic, multiflagellated sperm, they also concluded that