Human Reproduction, Vol. 18, No. 3, 653-654,
March 2003
© 2003 European Society of Human Reproduction and Embryology
What role does decreased ovarian reserve play in the aetiology of infertility related to endometriosis?
The University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School at Camden, Cooper Hospital/University Medical Center, Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, Camden, New Jersey, 7447 Old York Road, Melrose Park, PA 19027, USA. e-mail: laurie@ccivf.com
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Dear Sir,
I read with interest the manuscript ‘What is the optimal medical management of infertility and minor endometriosis: Analysis and future prospects’ (Cahill, 2002
). Dr Cahill concludes that the body of evidence supports the concept that some women’s fertility potential is adversely affected by this disorder. He presents data however that suggest that the association of endometriosis and infertility may be related to oocyte dysfunction possibly related to reduced LH concentrations in follicular fluid (Cahill et al., 1995; Verpoest et al., 2000) or glucocorticoid abnormalities in the follicular fluid (Smith et al., 2002). These abnormalities seem to be negated for the most part by correcting follicular maturation (Deaton et al., 1990; Mahmood et al., 1991; Fedele et