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Human Reproduction, Vol. 18, No. 5, 1129-1130, May 2003
© 2003 European Society of Human Reproduction and Embryology

Prions, urinary gonadotrophins and recombinant gonadotrophins

Roberto Matorras1 and Francisco Javier Rodríguez-Escudero

Human Reproduction Unit, Department of Obstetrics and Gynecology, País Vasco University, Hospital from Cruces, Baracaldo, Vizcaya, Spain

1 To whom correspondence should be addressed at: María Diaz de Haro, 7, 6i., 48013 Bilbao, Spain. e-mail: rmatorras@hcru.osakidetza.net

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Dear Sir,

The lack of reported cases of variant Creutzfeld-Jakob disease (vCJD) associated with urinary gonadotrophins is not a proof of their safety. One should bear in mind that vCJD incidence is 1 x 106 (at any one point in time), which translates to a lifetime risk of 1 x 104. On the other hand vCJD was first described in 1996 . . . [Full Text of this Article]


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