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Human Reproduction, Vol. 18, No. 6, 1357-1358, June 2003
© 2003 European Society of Human Reproduction and Embryology

Effects of LH on oocyte yield and developmental competence

Marco Filicori1, Graciela E. Cognigni and Walter Ciampaglia

Reproductive Endocrinology Center, University of Bologna, Via Massarenti 13, 40138, Bologna, Italy

1 To whom correspondence should be addressed. e-mail: marco.filicori@med.unibo.it

The first 10% of the full text of this article appears below.

Dear Sir,

Tesarik and Mendoza (2002Go) found that LH activity supplementation in oocyte donors enhanced FSH-induced folliculogenesis and increased the number of retrieved oocytes; conversely, exogenous LH administration appeared to negatively affect embryo morphology and implantation rates in subjects who had serum LH levels >=1 IU/l after steroid and GnRH agonist suppression. However, this interesting article failed to address a number of critical methodological and conceptual issues.

In this study hMG was used to supplement LH. Nevertheless, hCG also significantly contributes to the LH activity content of the hMG preparation used by the authors (Filicori et al., 2001Go), and hCG is detectable in peripheral serum after the administration . . . [Full Text of this Article]


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[Abstract] [Full Text] [PDF]