Human Reproduction, Vol. 18, No. 8, 1753-1755,
August 2003
© 2003 European Society of Human Reproduction and Embryology
Higher mole and lower dizygotic twin rate in Japan: are these oddities associated with the same reproductive errors?
Center for Demographic Studies, Duke University, 2117 Campus Drive, Durham, NC 27708, USA e-mail: mgolub@cds.duke.edu
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Dear Sir,
There are two well-recognized enigmas in the ethnic reproductive pattern: higher hydatidiform mole (HM) incidence and lower dizygotic (DZ) twin rate in some South-East Asian countries in comparison with populations of Europe and the USA (Bortolus et al., 1999
). A recent paper by Matsui et al. (2003) adds new important insights in the understanding of the first puzzle. The authors presented comprehensive data that incidence of HM per 1000 live births in Japan was rather high and
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