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Hum. Reprod. Advance Access originally published online on October 7, 2004
Human Reproduction 2004 19(11):2615-2618; doi:10.1093/humrep/deh470
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Human Reproduction vol. 19 no. 11 © European Society of Human Reproduction and Embryology 2004; all rights reserved

Uterine Doppler studies: technology driven data, or answers to our pathophysiological queries?

Associate Editor's comment on ‘Endometrial and sub-endometrial perfusion are impaired in women with unexplained subfertility’ by Raine-Fleming et al.

Dominique de Ziegler

Division of Reproductive Endocrinology and Infertility Department, Ob/Gyn University Hospital Geneva, 1211 Geneve, Switzerland

Correspondence to.Email: ddeziegler@bluewin.ch

The first 150 words of the full text of this article appear below.


   Getting over the teething of new technologies
 
Knowledge in medicine has always depended on the investigative tools available at any given time. This explains that our understanding of pathophysiology has most often progressed by frog leaps, reflecting the successive technological innovations bestowed upon the various fields of medicine, such as ours. The integration of new technological innovations normally follows a standard process whereby the new tools are first tested and their potential virtues tried out in sets of pilot and feasibility trials. This preliminary step normally offers a clearer view of the novel technologies' actual merits, potential clinical applications and usefulness for answering outstanding pathophysiological queries.

In the case of uterine Doppler however, we seem to be still at the first step of this process, dealing today with proof of principle trials that attempt to delineate the potential uses and applications of uterine Doppler in gynecology. It sometimes seems that uterine Doppler never succeeded in leaving the . . . [Full Text of this Article]


   Menopause and controlled ovarian stimulation (COH): divergent data with unanswered questions
 

   The ‘3rd factor hypothesis’ for explaining the low perfusion cases encountered in COH
 

   Differences in uterine Doppler data linked to fertility vanishing with time, while Doppler measurements moved down the vascular tree
 

   3-D power Doppler: a story revisited with quantified and reproducible measurements
 

   Back to the future of Doppler studies and the long-lived pilot trial time
 

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