Human Reproduction, Vol. 19, No. 2, 463-464,
February 2004
© 2004 European Society of Human Reproduction and Embryology
What is the LH ceiling level for follicular growth arrest in late follicular phase?
1 Section of Reproductive Medicine, Department of Obstetrics and Gynecology, Taichung Veterans General Hospital, Taichung and 2 Department of Obstetrics and Gynecology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan
3 To whom correspondence should be addressed at: 160 Chung-Kang Rd, Section 3, Taichung, Taiwan 407, Republic of China. E-mail: k388@vghtc.gov.tw
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Dear Sir,
We read the article by Loumaye et al. (2003
) with interest. They drew a conclusion that recombinant (r)LH alone can trigger follicular growth arrest in suggesting the existence of an LH ceiling during late follicular maturation. The authors showed that almost one third of patients had follicular growth arrest in the rLH-administered groups; conversely, the follicles persisted in growing in the control groups. While the authors administered 225 IU/day or 450 IU/day of rLH in World Health Organization (WHO) type I and type II patients, they did not come to a conclusion