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Human Reproduction, Vol. 19, No. 4, 1036-1037, April 2004
© 2004 European Society of Human Reproduction and Embryology

The ovopathy concept for explaining the secondary sex ratio

P.H. Jongbloet

Department of Epidemiology and Biostatistics, University Medical Centre Nijmegen, PO Box 9101, 6500 HB Nijmegen, The Netherlands e-mail: p.jongbloet@epib.umcn.nl

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Dear Sir,

We thank James for his remarks on the statement of our hypothesis (James, 2004Go). According to him, our line of reasoning would not imply decisively that the ovopathy concept for explaining the secondary sex ratio (SSR) variation would be false, but, I summarize: (i) he disagrees with our statement that some adverse circumstances associated with female offspring have led to involvement of the notions of SSR ‘reversal’ and ‘inverted dose–response gradient’, which would suggest ‘a circular argument, i.e. one that assumes what is purportedly being demonstrated’; (ii) I would be unable to predict the SSR changes predicted by him, and particularly not in which direction; (iii) the data on the sexes of associated abortions would be needed in order to learn whether ‘sex ratio reversal’ occurs in . . . [Full Text of this Article]


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