Hum. Reprod. Advance Access originally published online on February 25, 2005
Human Reproduction 2005 20(5):1292-1297; doi:10.1093/humrep/deh785
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The couple's decision-making in IVF: one or two embryos at transfer?
1 In Vitro Fertilization Clinic, S-791 82 Falun, 2 Centre for Clinical Research, S-791 82 Falun, 3 Dalarna University College, S-791 82 Falun and 4 Department of Obstetrics and Gynecology, Falun Hospital, S-791 82 Falun, Sweden
5 To whom correspondence should be addressed. Email: maria.blennborn{at}ltdalarna.se
BACKGROUND: The aim of this study was to evaluate the decision-making process and factors that contribute to the decision of IVF participants to choose one or two embryos at transfer. METHODS: Two hundred and seventy-four IVF patients equally distributed in males and females were personally interviewed using a semi-structured questionnaire which included 82 items. RESULTS: In the whole study population, previous childbirth [odds ratio (OR) 2.1; 95% confidence interval (CI) 1.9–3.6], and spare embryos to freeze (OR 23.6; 95% CI 11.2–54.5) emerged as the most important variables in patients who had one embryo transferred, while previous IVF treatments (OR 0.3; 95% CI 0.1–0.6) and the assumed increased pregnancy chance (OR 0.1; 95% CI 0.05–0.3) were the most important decision-making factors among those who had two embryos. The women were more satisfied with the information (83 versus 71%; P=0.02), and more aware of the risks with twin pregnancies (77 versus 66%; P=0.03) than the males. The women were also more concerned about their age. Knowledge about risks of multiple pregnancies was higher in females (77%) than in males (66%, P=0.03). CONCLUSION: The results of this study indicate that despite good information about the risks for complications with multiple pregnancies, many patients wish to have two embryos transferred. Spare embryos to freeze, improvement of pregnancy rate in single embryo transfer and young age of the woman are predictive of choosing single embryo transfer. However, the final decision must always be made in agreement with the physician.
Key words: double embryo transfer/IVF/patient's decision-making/single embryo transfer
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