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Hum. Reprod. Advance Access originally published online on April 7, 2005
Human Reproduction 2005 20(8):2253-2260; doi:10.1093/humrep/dei015
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© The Author 2005. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: journals.permissions{at}oupjournals.org

A longitudinal, prospective study on emotional adjustment before, during and after consecutive fertility treatment cycles

C.M. Verhaak1,4, J.M.J. Smeenk2, A. van Minnen3, J.A.M. Kremer2 and F.W. Kraaimaat1

1 Department of Medical Psychology, 2 Department of Obstetrics and Gynaecology, University Medical Centre St Radboud, Nijmegen, P.O.Box 9101, 6500 HB Nijmegen and 3 Department of Clinical Psychology, University of Nijmegen, Nijmegen, The Netherlands

4 To whom correspondence should be addressed. Email: c.verhaak{at}cukz.umcn.nl

BACKGROUND: A longitudinal study into the course of the emotional response to IVF from pre-treatment to 6 months post-treatment and factors that contributed to that course. METHODS: A total of 148 IVF patients and 71 partners completed self-report questionnaires on anxiety, depression, personality characteristics, meaning of fertility problems, coping, marital relationship and social support at pre-treatment. Assessments of anxiety and depression were repeated immediately following the final treatment cycle and again 6 months later (follow-up). RESULTS: Women showed an increase of both anxiety and depression after unsuccessful treatment and a decrease after successful treatment. Men showed no change in anxiety and depression either after successful or after unsuccessful treatment. In the 6 months after unsuccessful treatment, women showed no recovery. At follow-up, >20% of the women showed subclinical forms of anxiety and/or depression. Personality characteristics, meaning of the fertility problems, and social support determined the course of the emotional response. CONCLUSIONS: Most women adjusted well to unsuccessful treatment, but at follow-up, a considerable proportion still showed substantial emotional problems. Personality characteristics, pre-treatment meaning of the fertility problems and social support have demonstrated the adjustment to unsuccessful IVF in women. This allows early identification of women at risk as well as tailored interventions.

Key words: anxiety/depression/IVF/longitudinal study/prospective study


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